In the context of increasingly strong globalization, countries around the world give priority to promoting innovative start-ups. For Vietnam, 2016 was chosen as the year of "Start-up Nation", which shows that the issue of entrepreneurship is receiving special attention from the State and society. One of the urgent issues to help innovative start-ups develop quickly and strongly in the current context is to develop, perfect and well implement policies to support innovative start-ups. Although there have been some initial successes, start-up activities in our country still face many difficulties, development is still not systematic. The article briefly introduces the policy of supporting innovative start-ups of the Party and State of Vietnam. On the basis of the achieved results and existing limitations, to propose solutions to promote innovative start-ups increasing in quantity and quality, contributing to helping creative startups in Vietnam. Nam will be more successful in the future.