The maxillary artery is the largest branch of the external carotid artery in the neck. It passes through the infratemporal fossa and is a major source of blood supply for the nasal cavity, oral cavity, all teeth, and the dura mater in the cranial cavity. However, in Viet Nam, studies relating to the anatomy of the maxillary artery still have limitations. Objective: To investigate the course in relation to the lateral pterygoid muscle and main branches features of the maxillary artery in the infratemporal fossa. Methods: Cross-sectional descriptive study. From September 2020 to June 2021, we examined 20 infratemporal fossae in fresh cadaveric samples at The Anatomy Department – University of Medicine and Pharmacy at HCM city and recorded the features of the maxillary arteries. Results: 90 percent of maxillary arteries are superficial to lateral pterygoid muscle. The mean diameter of middle meningeal arteries, inferior alveolar arteries and masseteric arteries is 2,08 ± 0,17 mm; 1,12 ± 0,17 mm and 0,87 ± 0,18 mm respectively. The mean distance from the mandible triangle to the origin of middle meningeal arteries, inferior alveolar arteries, and masseteric arteries is 40,07 ± 1,78 mm; 36,38 ± 1,56 mm và 43,50 ± 3,07 mm correspondingly. Discussion: The Feature of the maxillary artery varies and our results are almost similar to previous studies. Knowledge about the anatomy of maxillary artery wanes hemorrhagic complications when manipulating in the infratemporal fossa surgery.