Gastrostomy is performed when need feeding the patient through the gastrointestinal tract but cannot eat orally. Nowadays, gastric bypass is mostly done endoscopically, but not every case is possible. In order to nourish esophageal cancer patients who need neoadjuvant chemoradiotherapy and use the stomach to replace the esophagus when performing esophagectomy after chemoradiotherapy treatment, we performed the technique laparoscopic gastrostomy from the anterior wall of the stomach. The surgery results were successful in all patients, with operative times ranging from 20 to 45 minutes. There were no cases of accidents and complications. The patient was nourished again by the gastrointestinal tract after 24 hours and transferred to the chemoradiotherapy department after 3 to 4 days for neoadjuvant chemoradiotherapy treatment. Methods: This is a prospective interventional study on a group of patients with esophageal cancer, who are indicated for neoadjuvant chemoradiotherapy and for large tumors that cannot undergo endoscopic gastrostomy. Results: During the period from April 2021 to May 2022, we performed laparoscopic gastrostomy for 5 patients with the lower third of the esophagus cancer, who have had cT3N0M0 disease stage. These patients were characterized by cannot eat or drink by mouth because a large tumor makes obstructed the lumen of the esophagus. Conclusion: Laparoscopic gastrostomy from the anterior wall of the stomach is a safe technique, with short operation time and quick postoperative recovery.