Almost inpatients who are suffer from blood disoder diseases are transfused many times. Study on irregular antibodies' ratio and characteristic in these patients is necessary to have effective methods to reduce transfusion reactions then perform effective transfusion to these patient. Objectives: Study on irregular antibody ratio and characteristic in patients who were suffer from blood disoder diseases in NIHBT from 2009 to 2011. Materials: 2.293 patients who were treated in NIHBT from December 2009 to April 2011, patients' age from 7 to 91 years old. Methods: Using gelcard method on Hemos SPII automachine system with screening cell and panel cell which were made in NIHBT to detect patients' irregular antibodies. Results: The authors found out 130 patients have irregular antibodies among 2.293 patients (made up 5.7 percent). The highest irregular antibodies ratio was found in Rh blood group system: 46.5 percent (Anti-E: 29.2 percent; anti-c: 15.2 percent; anti-C: 0.6 percent), anti-Mia of MNS blood group system made up 34 percent, Kidd's antibodies, Duffy's antibodies, P's antibodies and Lewis's antibodies made up lower ratio. Irregular antibody ratio in woman patients is higher than man patients (man: 4.8 percent, woman: 6.7 percent). Irregular antibody ratio related to transfusion times (less than 5 times: 2.4 percent; from 5 to 10 times: 6.4 percent; more than 10 times: 10.8 percent). Myelodysplastic syndrome patients have the highest irregular antibody ratio. Conclusions: Irregular antibody ratio of patients who were suffer from blood disoder diseases is 5.7 percent. The highest irregular antibodies ratio was found in Rh blood group system: 46.5 percent, anti-Mia of MNS blood group system made up 34 percent. Irregular antibody ratio related to sex and transfusion times. The highest irregular antibodies ratio was found in myelodysplastic syndrome patients and thalassaemia patients.
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