The effect of stocking density of white leg shrimp SPF (Litopenaeus vannamei) was carried out at different density of 40, 60 and 80 PL 15/m2 for 75 days. Each treatment was replicated three times in 4m2 indoor composite tank system and feeding ratio of 10-15 percent body weight with CP pellets containing 38 percent crude protein and four times a day. During the experiment, water temperature varied between 28 and 31°C, whereas salinity ranged from 20-24 thousandth in biosecurity condition. Water in the culture tanks was renewed 50 percent weekly. The highest growth rate in weight was found in treatment of 40 heads/m2 (1.54 g/week), followed by 60 heads/m2 (1.47 g/week) but the rate for 30 heads/m2 (1.16 g/week) was lowest. Similarly, the survival rate of shrimp stocking at 40 heads/m2 ranked highest (79.7 + or - 2.6 percent), followed by 60 heads/m2 (78.7 + or - 2.9 percent) and the lowest rate for the 80 heads/m2 (70.3 + or - 3.3 percent; P0.05). Nevertheless, there was no significant difference in the survival rate between shrimp raised at 40 heads/m2 and 60 heads/m2 (P0.05). Size variation (CV) for 40 heads/m2 (7.27 + or - 1.52 percent) and 60 heads/m2 (8.22 + or - 2.5 percent) were considerably lower than that for 80 heads/m2 (12.9 + or - 2.7 percent; P0.05). However, there was no considerable disparity in feed conversion rate among the three treatments (P0.05). All shrimp sample tissues were found negative for WSSV, YHV, TSV, MBV and IHHNV.