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Đào Lan Hương; Nguyễn Viết Tiến; Nguyễn Viết Tiến(1)

Tìm hiểu một số yếu tố liên quan đến kết quả thụ tinh ống nghiệm của bệnh nhân đáp ứng kém với kích thích buồng trứng tại bệnh viện Phụ sản Trung ương năm 2011

Research some factors related to results of in vitro fertilization of poor responders to ovarian stimulation in National hospital of obstetrics and gynecology (NHOG), 2011

Thông tin Y dược

2012

11

25-27

0868-3891

Thụ tinh ống nghiệm; Đáp ứng kém kích thích buồng trứng; Yếu tố liên quan

Objectives: Research some factors related to results of in vitro fertilization of patients who were poor response to ovarian stimulation in NHOG. Methods: The retrospedjve study desclibed the profile of 612 in vitro fertilization patients in NHOG who were diagnosed as poor responder to ovatian stimulation in one year from January, 2011 to December, 2011. Results: The average age of patients was 34.65 percent + or - 4.78; mean FSH in the 3th day is 7.43x2.89 mIU/ml; average of oestradiol (E2) in the 3th day was 64.16 + or - 4.69 pg/ml Antral follide count (AFC) was 6.21 + or 3.58. Pregnancy rate of poor responder group was 16.46 percent. cyde cancellation rate was 8.66 percent. For patients under 35 years old, the pregnancy rate was 2.06 times higher than the group of patients who were older than 35. Group of patients with FSH levels 10 mIU/ml in the 3th day has pregnancy rate 2.87 times higher compared with group which had FSH levels 10 mJU/ml in the 3th day, the dinical pregnancy rate in group which AFC 5 was 2.34 times higher than the group which AFC 5; and the pregnancy rate of group whose lining of the uterus thickness 10 mm is 2.34 times higher than those 10 mm. Condusions: Age, level of FSH in the 3th day, AFC; lining of the uterus thickness are prognostic factors of poor response and dosely relate to the results of vitro fertilization.

TTKHCNQG, CVv161