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104.01-2020.01

2023-53-0677/NS-KQNC

Nghiên cứu tổng hợp các hợp chất lai trên cơ sở 1H-123-triazole và một số dị vòng chứa nitơ và oxy

Trường Đại học Khoa học Tự nhiên

Đại học Quốc gia Hà Nội

Quốc gia

GS. TS. Nguyễn Đình Thành

TS. Nguyễn Thị Kim Giang, TS. Hoàng Thị Kim Vân, TS. Vũ Ngọc Toán, TS. Đỗ Sơn Hải

Hoá hữu cơ

01/10/2020

01/10/2023

29/03/2023

2023-53-0677/NS-KQNC

20/04/2023

Cục thông tin KH&CN Quốc gia

Đây là đề tài NCCB thuần tuý. Ket quả của nhiệm vụ được sử dụng tiếp trong các bài báo sau:

+ Wang, c., Zhang, Y., Zhang, T., Xu, J., Yan, s., Liang, B., & Xing, D. (2023). Epidermal growth factor receptor dual-target inhibitors as a novel therapy for cancer: A review. International Journal of Biological Macromolecules, 127440.

+ Yildirim, Metin, Samet Poyraz, and Mehmet Ersatir. "Recent advances on biologically active coumarin-based hybrid compounds." Medicinal Chemistry Research 32.4 (2023): 617- 642.

+ Nguyen, H.T., Tuan, A.N., Thi, T.A.D., Van, K.T., Le-Nhat-Thuy, G., Thi, P.H., Thi, Q.G.N., Thi, C.B., Quang, H.T. and Van Nguyen, T., 2024. Synthesis, in vitro a-glucosidase, and acetylcholinesterase inhibitory activities of novel indol-fused pyrano [2, 3-d] pyrimidine compounds. Bioorganic & Medicinal Chemistry Letters, 98, p. 129566.

+ Singh, K., Tyagi, R., Mishra, V. K., Tiwari, G., & Sagar, R. (2023). Recent advances in the synthesis of bioactive glycohybrids via click-chemistry. SynOpen, 7(03), 322-352.

+ Mamidala, A., Bokkala, K., Thirukovela, N. s., Sirassu, N., Bandari, s., & Nukala, s. K. (2022). Synthesis of Quinoline-Morpholine-Coupled 1, 2, 3-Triazole Hybrids as In vitro EGFR inhibitors. ChemistrySelect, 7(47), e202203763

+ Song, J., Zhang, s., Zhang, B., & Ma, J. (2023). The anti-breast cancer therapeutic potential of 1, 2, 3-triazole-containing hybrids. Archiv der Pharmazie, e2300641.

+ Tran, Due Quan, Ngoc Hung Truong, Thi Hoang Anil Nguyen, Thi Thuy Trinh, Thi Cham Ba, Thi Thuy Linh Nguyen, Van Tu Ngo, Thi Inh Cam, Minh Quan Pham, and Van Chinh Luu. "Dihydroartemisinin and zerumbone esters of ataluren and its analogs as anticancer agents and EGFR inhibitors." Journal of Chemical Research 47, no. 6 (2023): 17475198231219451.

+ Cheng, s., Zou, Y., Chen, X., Chen, J., Wang, B., Tian, J.,... & Zhang, D. (2023). Design, synthesis and biological evaluation of 3-substituted-2-thioxothiazolidin-4-one (rhodanine) derivatives as antitubercular agents against Mycobacterium tuberculosis protein tyrosine phosphatase B. European Journal of Medicinal Chemistry, 115571.

+ Aitha, Shalini, Vishnu Thumma, Raghavender Matta, Shankaraiah Ambala, K. Jyothi, Srinivas Manda, and Jalapathi Pochampally. "Antioxidant Activity of Novel 4H-Chromene Tethered 1, 2, 3-Triazole Analogues: Synthesis and Molecular Docking Studies." Results in Chemistry (2023): 100987.

+ Aitha, Shalini, Vishnu Thumma, Raghavender Matta, Shankaraiah Ambala, K. Jyothi, Srinivas Manda, and Jalapathi Pochampally. "Results in Chemistry."

+ Trivedi, Komal, Sanjeev R. Kane, ư. K. Goutam, Himanshu Srivastava, and Chetan K. Modi. "Single-pot modus operandi for 2-amino-4H-chromenes synthesis utilizing amine functionalized graphene oxide decorated with zirconium oxide." Molecular Catalysis 550 (2023): 113591.

+ Azad Poshtmakhi, Sedigheh, Kurosh Rad-Moghadam, Hedyeh Hosseinzadeh, and Saeedeh Toorchi-Roudsari. "Finely Dispersed Fe3O4 and Ag Nanoparticles Adhered by Starch Nano layers: an Efficient Catalyst for the Synthesis of Pyrano [2, 3-d] Pyrimidines." ChemistrySelect 8, no. 45 (2023): e202300533.

+ Selvaraj, L., Eswaran, R., Natesan, V. K., & Muthu, s. p. (2024). Tandem aqueous extract of onion catalyzed Knoevenagel condensation-Michael addition-cyclization: A green synthesis of 2-amino-3-cyano-4H-pyran derivatives and their anti-oxidant and molecular docking studies. Journal of Molecular Structure, 1302, 137373.

+ Engel, Matthias, Reem K. Fathalla, and Christian Ducho. "Inhibitors of the bacterial enzyme MurA as potential novel antibiotics." (2023).

+Singh, Atamjit, Karanvir Singh, Aman Sharma, Jasleen Kaur, Ramanpreet Kaur, Jashandeep Kaur, Kirandeep Kaur, Renu Chadha, and Preet Mohinder Singh Bedi. "Rational utilization of 1, 2, 3-triazole scaffold in anti-MRSA drug development: Design strategies, Structural insights and Pharmacological outcomes." Journal of Molecular Structure (2023): 136557.

+ Singh, Gurjaspreet, Anita Devi, Anamika Saini, Jashan Deep Kaur, and Sofia Gupta. "Synthesis,“turn-on” fluorescence signals towards Zn 2+ and Hg 2+ and monoamine oxidase A inhibitory activity using a molecular docking approach of morpholine analogue Schiff base linked organosilanes." New Journal of Chemistry 46, no. 45 (2022): 21717-21729.

+ Esmaili, Soheila, Ahmad Ebadi, Ardeshir Khazaei, Hamideh Ghorbani, Mohammad All Faramarzi, Somayeh Mojtabavi, Mohammad Mahdavi, and Zahra Najafi. "Novel Pyrano [3, 2-c] quinoline-1, 2, 3-triazole Hybrids as Potential Anti-Diabetic Agents: In Vitro a- Glucosidase Inhibition, Kinetic, and Molecular Dynamics Simulation." ACS Omega (2023).

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