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Dương Thị Anh Đào; Lê Thị Tuyết; Nguyễn Thị Hồng Hạnh; Nguyễn Thị Trung Thu; Lê Thị Anh; Lê Thị Tuyết(1);  Nguyễn Thị Hồng Hạnh(2); 

Tác dụng điều trị béo phì và rối loạn lipid máu của dịch chiết lá sen (nelumbo nucifera) trên chuột nhắt trắng ăn chế độ ăn giàu chất béo

Treating for obesity mice by using lotus (Neulumbo nucifera) leaf tea

Khoa học

2013

3

122-132

0868-3719

Dịch chiết lá sen; Tác dụng điều trị; Béo phì; Rối loạn lipid máu; Chuột nhắt trắng thực nghiệm

The aim of this study was to investigate the effects of lotus leaf tea in obesity treatment. Mice were divided into three experimental groups (32 mice per group): the control group (DC) consisted of normal mice that were fed a basic diet while the first experimental group was fed a high fat diet (BP) and the second experimental group (DT) was fed a high fat diet and given 25 ml lotus leaf tea/kg body weight per day. The mice were weighed weekly. Blood lipids were measured in the 6th and 9th week. Histological samples of liver and arterial tissues were taken in the 9th week. The results showed that regarding body weight and blood lipid levels: the triglycerides (TG), total cholesterol (TC) and low density lipoprotein-cholesterol (LDL - C) of mice fed DT diets was significantly lower than those mice which were fed a DC diet. In liver and arterial tissues of mice in DT groups, large lipid droplets were not seen and the number of droplets was fewer compared to mice in the BP group. Doses of 200 and 250 mL leaf tea/kg body weight per day were more effective in treating obesity than doses of 50 and 100 ml leaf tea/kg body weight per day.

TTKHCNQG, CVv157

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